Dobzhansky-Muller incompatibilities in protein evolution
نویسندگان
چکیده
منابع مشابه
Emergent Speciation by Multiple Dobzhansky–Muller Incompatibilities
The Dobzhansky–Muller model posits that incompatibilities between alleles at different loci cause speciation. However, it is known that if the alleles involved in a Dobzhansky–Muller incompatibility (DMI) between two loci are neutral, the resulting reproductive isolation cannot be maintained in the presence of either mutation or gene flow. Here we show that speciation can emerge through the col...
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Evolution in allopatric populations can lead to incompatibilities that result in reduced hybrid fitness and ultimately reproductive isolation upon secondary contact. The Dobzhansky-Muller (DM) model nicely accounts for the evolution of such incompatibilities. Although DM incompatibilities were originally conceived as resulting of interactions between nuclear genes, recent studies have documente...
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The Dobzhansky–Muller model posits that incompatibilities between alleles at different loci 5 cause speciation. However, it is known that if the alleles involved in a Dobzhansky–Muller 6 incompatibility (DMI) between two loci are neutral, the resulting reproductive isolation cannot 7 be maintained in the presence of either mutation or gene flow. Here we propose that speciation 8 can emerge thro...
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Speciation is characterized by the development of reproductive isolating barriers between diverging groups. Intrinsic post-zygotic barriers of the type envisioned by Bateson, Dobzhansky, and Muller are deleterious epistatic interactions among loci that reduce hybrid fitness, leading to reproductive isolation. The first formal population genetic model of the development of these barriers was pub...
متن کاملGENETICS | INVESTIGATION Signatures of Dobzhansky-Muller Incompatibilities in the Genomes of Recombinant Inbred Lines
In the construction of Recombinant Inbred Lines (RILs) from two divergent inbred parents certain genotype (or epigenotype) combinations may be functionally “incompatible” when brought together in the genomes of the progeny, thus resulting in sterility or lower fertility. Natural selection against these epistatic combinations during inbreeding can change haplotype frequencies and distort linkage...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.232565499